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Nanjing Norman Biological Technology Co., Ltd
Nanjing Norman Biological Technology Co., Ltd  

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You are here: home  > Immunofluorescence Reagents  > Immunofluorescence Gastrosis kits  > Diagnostic Test Kits For PGⅡassay

Diagnostic Test Kits For PGⅡassay 

Payment Terms: T/T,L/C,D/A,D/P,WU,Paypal,Money Gram 
Place of Origin: Jiangsu, China (Mainland) 
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Product Detail

Model No.: NRM-FI-1000
Production Capacity: 1,000,000.00/Mon
Delivery Date: TWO WEEKS AFTER PAYMENT
Methodology: Fluorescence Immunoassay
Test time: 15mins
Manufacturer: Independent R & D
Delivery Detail: depend on quantity
Means of Transport: Ocean,Land,Air
Packing: IN CARTON
Brand Name: Norman
Place of Origin: Jiangsu, China (Mainland)
Specimen: serum
Service: International after-sales
Type: NRM-FI-1000

PG II
1.The status and function of gastric mucosa.
2.Dynamic detection of gastric function.
3.Early screening of gastric cancer.

            Diagnostic Test Kits For PGⅡ Reagent


Methodology                                                                                 

Fluorescence Immunoassay


Product Name: PGII                                                                  


1.The status and function of gastric mucosa.

2.Dynamic detection of gastric function.

3.Early screening of gastric cancer.


Package                                                                                           


Test card: Aluminum foil pouch 1pc/bag, desiccant

Package size: 25pcs/box




PGII serum specs                                                                       


Methodology

Fluorescence Immunoassay

Specimen

serum

Measuring range

2-70ng/ml

Cut-off value

2ng/ml

Reaction time

15 minutes

Shelf life

12months


Intended use                                                                                

The test kit is primarily for the in vitro quantitative determination of PGⅡ content in

human blood serum. Pepsinogen  (PG) is precursor of pepsin. According to distribution 

and immunogenicity,  it is divided into PGⅡand PGⅡ. Most of gastric mucosa synthesis

pepsinogen are into stomach cavity and about 1% of pepsinogen are into blood. 


The content of PG in serum reflects its secretion level and the level of serum PG reflects 

the form and function of different parts of gastric mucosa. The correlation of PGⅡis larger 

with gastric mucosal lesions (relative to the distal gastric mucosa). Its rising relates to 

fundic gland atrophy, gastric metaplasia, pseudopyloric metaplasia and dysplasia. The 

processive reducing of ratio PGⅠ/Ⅱ relates to gastric mucosal atrophy.


The ratio of PGⅠand PGⅡ(PGR) has the effect of "Serological biopsy" for gastric mucosa.

It is one of the effective ways for monitoring gastric mucosa lesion such as gastritis, gastric

ulcer and etc, estimating the process of atrophic gastritis. 


Principle of the Procedure                                                     

The reagent is based on immunefluorescence sandwich assay to detect PGⅡ concentrations quantitatively. Using the pipette provided, drop diluted sample into the sample well. During testing, specimen reacts with the particles coated with anti- PGⅡ monoclonal antibody I which has conjugated with fluorescent latex. The mixture migrates upward on the nitrocellulose membrane by capillary action to react with anti- PGⅡ monoclonal antibody II on the test line. The intensity of fluorescent antibody signal reflects the amount of captured PGⅡ. Immunefluorescence quantitative analyzer produced by our company can detect the concentration of PGⅡ in the sample.




Clinical Significance                                                                  


1.Atrophy of gastric fundus gland duct.

2.Intestinal metaplasia.

3.Pseudopyloric metaplasia.

4.Evaluation indicator of gastric cancer.


Advantage                                                                                      


1.High sensitivity:2ng/ml.

2.Overall evaluation: evaluate PGI and PGI/PGII.

3.Small sample size: 30ul (serum).

4.Wide linear range:2-70ng/ml.


Performance Analysis                                                               

Correlation analysis between Norman PGII and Abbott PGII.



Applicable Department                                                           

Gastroenterology, internal medicine, surgery, traditional Chinese medicine.


Product Show                                                                              


Package & Delivery                                                                    


Agent Wanted                                                                              

If you are interested in working with us, please feel free to contact.


bigPhoto
 Ms. Ying Qin
Department Manager
Tel: 86-25-58602219
Mobile: 138 1471 7578
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Company Info

Nanjing Norman Biological Technology Co., Ltd [China (Mainland)]


Business Type:Manufacturer
City: Nanjing
Province/State: Jiangsu
Country/Region: China (Mainland)

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